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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1003819Generated: November 3, 2026

Imidazole → HCID 18798645, compound

https://huagongshe.com/reaction/1003819

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
Reactanttert-Butyldimethylsilyl chlorideHCID 28928—
ReactantHCID 12648138HCID 12648138—
SolventDichloromethaneHCID 6344—
ProductHCID 18798645HCID 18798645—

Reaction Steps

The title compound was prepared as described in General Method 5 using 4.11 g (18.2 mmol) of 3-(3-hydroxy-phenyl)-1-phenyl-propan-1-one from Example M, 1.5 g (22 mmol) of imidazole, 3.0 g (20 mmol) of t-butyldimethylsilyl chloride and 75 mL of CH2Cl2. The product was carried on crude to the next step (see Example UU).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06046355
Source datasetuspto-grants-2000_04
ORD IDord-0e646a23d7a741bab413f03aad8c3be3
Source noteuspto-grants-2000_04