反应详情

3,5-Dimethoxyiodobenzene (1.19 g) is dissolved in acetic acid (10 ml), and thereto is added 47% hydrobromic acid (10 ml) at room temperature, and the mixture is refluxed for 15 hours. The reaction mixture is cooled to room temperature, and concentrated to dryness under reduced pressure. The residue is dissolved in ethyl acetate, and the organic layer is washed with water, dried, and concentrated under reduced pressure to give 3,5-dihydroxyiodobenzene (1.06 g).

1. temperaturethe mixture is refluxed for 15 hours
2. concentrationconcentrated to dryness under reduced pressure
3. dissolutionThe residue is dissolved in ethyl acetate
4. washthe organic layer is washed with water
5. customdried
6. concentrationconcentrated under reduced pressure