反应详情

3,5-Diacetoxystyrene (580 mg) is dissolved in a mixture of ethyl acetate (6 ml) and ethanol (2 ml), and the mixture is subjected to catalytic reduction with using 10% palladium-carbon (51.4% aqueous, 50 mg) under atmospheric pressure. Two hours thereafter, the catalyst is removed by filtration, and the filtrate is concentrated under reduced pressure. The residue is purified by silica gel column chromatography (solvent; hexane/ethyl acetate) to give 1,3-diacetoxy-5-ethylbenzene (450 mg).

1. customTwo hours thereafter, the catalyst is removed by filtration
2. concentrationthe filtrate is concentrated under reduced pressure
3. customThe residue is purified by silica gel column chromatography (solvent; hexane/ethyl acetate)