Ammonia → HCID 18470624, compound

HRID 1004025Notes

Reaction equation

HRID 1004025 reaction equation
[C:1]([C:3]1[C:8]([O:9][CH:10]2[CH2:14][CH2:13][CH2:12][CH2:11]2)=[C:7]([O:15][CH3:16])[C:6]([O:17][CH3:18])=[CH:5][C:4]=1[N+:19]([O-])=O)#[N:2].ClCCl.N>CO>[C:1]([C:3]1[C:8]([O:9][CH:10]2[CH2:14][CH2:13][CH2:12][CH2:11]2)=[C:7]([O:15][CH3:16])[C:6]([O:17][CH3:18])=[CH:5][C:4]=1[NH2:19])#[N:2]

Participants

5

Reactant 3

HCID 222AmmoniaHCID 6344DichloromethaneHCID 18470622HCID 18470622, compound

Product 1

HCID 18470624HCID 18470624, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The subtitle compound was prepared from 2-cyano-3-cyclopentyloxy-4,5-dimethoxynitrobenzene following the procedure described in Example 10(f) and was obtained as a cream coloured solid (66%). Rf 0.79 (dichloromethane:methanol:0.880 aqueous ammonia, 92:7:1, v/v). 1H-NMR (CDCl3): δ=1.57 (2H, m), 1.70 (2H, m), 1.90 (4H, m), 3.68 (3H, s), 3.82 (3H, s), 5.10 (1H, m), 5.98 (1H, s).

Workup

  1. customwas obtained as a cream

Sources & evidence

ORD record
ord-115ee2b154864174ae0f04fd411f6a58
Source dataset
uspto-grants-2000_04
Patent number
US06048864

Reaction notes

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