Methanol → HCID 54558571, compound

Participants

Reaction Steps

A solution of (4-amino-2-trifluoromethyl-phenyl)-acetic acid (0.082 g) in methanol (10 ml) containing concentrated sulphuric acid (0.1 ml) was heated under reflux for 2 h. The solution was cooled, concentrated, and partitioned between ethyl acetate and aqueous sodium carbonate solution. The organic phase was separated, dried, and concentrated to give the title compound as a yellow solid (0.089 g)

Provenance & Evidence