Water → Sodium (E)-3-[5,6-dimethoxy-3-(4-methoxyphenoxy)benzo[b]thiophen-2-yl]-2-(4-pyridinyl)-2-propenoate

Participants

Role	Name	HCID	Charge
Reactant	Water	HCID 962	—
Reactant	Sodium Hydroxide	HCID 14798	—
Reactant	(E)-3-[5,6Dimethoxy-3-(4-methoxyphenoxy)benzo[b]thiophen-2-yl]-2-(4-pyridinyl)-2-propenoic acid	HCID 9912231	—
Product	Sodium (E)-3-[5,6-dimethoxy-3-(4-methoxyphenoxy)benzo[b]thiophen-2-yl]-2-(4-pyridinyl)-2-propenoate	HCID 86755304	—

Reaction Steps

Water is added to a suspension of 1.16 g of the product of Example 2 in 2.5 ml of 1N sodium hydroxide solution until completely diluted. Lyophilisation enables 1.22 g of the expected product to be isolated.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06048875
Source dataset	uspto-grants-2000_04
ORD ID	ord-e91376d6017c4452969dc79bba313799
Source note	uspto-grants-2000_04