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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1004133Generated: October 30, 2026

2-(4-Fluorophenyl)oxybutyl bromide → 1-[4-(4-Fluorophenyl)oxybutyl]-4-(4-phenoxyphenyl)piperidine

https://huagongshe.com/reaction/1004133

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Fluorophenyl)oxybutyl bromideHCID 18412134—
Reactant(E)-1-[3-(4-hydroxy-3-methoxyphenyl)-2-propenyl]-4-(4-phenoxyphenyl)piperidineHCID 18412177—
Product1-[4-(4-Fluorophenyl)oxybutyl]-4-(4-phenoxyphenyl)piperidineHCID 18412137—

Reaction Steps

The same procedure was followed as in Example 11 using the compound (9) synthesized in Example 2 and 2-(4-fluorophenyl)oxybutyl bromide to produce the above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06048876
Source datasetuspto-grants-2000_04
ORD IDord-6ab07af4c99649eab029ed2bedeeff0a
Source noteuspto-grants-2000_04