Ethyl chloroformate → HCID 21264561, compound

HRID 1004151Notes

Reaction equation

HRID 1004151 reaction equation
[CH3:1][C:2]1[N:3]([CH2:7][C:8]2[CH:13]=[CH:12][C:11]([N+:14]([O-:16])=[O:15])=[CH:10][CH:9]=2)[CH:4]=[CH:5][N:6]=1.Cl[C:18]([O:20][CH2:21][CH3:22])=[O:19]>C(N(CC)CC)C>[N+:14]([C:11]1[CH:10]=[CH:9][C:8]([CH2:7][N:3]2[CH:4]=[CH:5][N:6]=[C:2]2[CH2:1][C:18]([O:20][CH2:21][CH3:22])=[O:19])=[CH:13][CH:12]=1)([O-:16])=[O:15]

Participants

4

Reactant 2

HCID 10928Ethyl chloroformateHCID 50471292-Methyl-1-(4-nitrobenzyl)-1H-imidazole

Product 1

HCID 21264561HCID 21264561, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

24.8 g of 2-methyl-1-(4-nitrobenzyl)imidazole was reacted with 22 ml of ethyl chloroformate in the presence of 32 ml of triethylamine to obtain 13.9 g of ethyl 1-(4-nitrobenzyl)imidazol-2-ylacetate.

Sources & evidence

ORD record
ord-8c7c224a8b334c8ab299a8e8551f9294
Source dataset
uspto-grants-2000_04
Patent number
US06048884

Reaction notes

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