Hydrochloric Acid → 4-Amidinobenzoic acid hydrochloride

HRID 1004502Notes

Reaction equation

HRID 1004502 reaction equation
[C:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8](N)=[O:9])=[CH:6][CH:5]=1)(=[NH:3])[NH2:2].[ClH:13].[OH2:14]>>[ClH:13].[C:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8]([OH:14])=[O:9])=[CH:6][CH:5]=1)(=[NH:3])[NH2:2]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 5960194-Amidinobenzamide

Product 1

HCID 448908304-Amidinobenzoic acid hydrochloride

Procedure

4-Amidinobenzamide (commercially available one, 7.8 g) is dissolved in water (200 ml), and thereto is added conc. hydrochloric acid (200 ml), and the mixture is stirred at a temperature below 100° C. for 9 hours. The mixture is cooled, and the precipitated crystals are collected by filtration.

Workup

  1. temperatureThe mixture is cooled
  2. filtrationthe precipitated crystals are collected by filtration

Sources & evidence

ORD record
ord-3163d9fb240a4fba860545ef48b98d52
Source dataset
uspto-grants-2000_04
Patent number
US06048854

Reaction notes

Loading…