Cyclohexylhydroxylamine → N-Cyclohexyl-alpha-(2sulfofuran-5-yl)nitrone

HRID 1004560Notes

Reaction equation

HRID 1004560 reaction equation
[CH:1]([C:3]1[O:7][C:6]([S:8]([OH:11])(=[O:10])=[O:9])=[CH:5][CH:4]=1)=O.[Na].[CH:13]1([NH:19][OH:20])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1>>[CH:13]1([N+:19]([O-:20])=[CH:1][C:3]2[O:7][C:6]([S:8]([OH:11])(=[O:10])=[O:9])=[CH:5][CH:4]=2)[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1

Participants

4

Reactant 3

HCID 72935CyclohexylhydroxylamineHCID 27240012-Formylfuran-5-sulfonateHCID 5360545Sodium2×

Product 1

HCID 85040086N-Cyclohexyl-alpha-(2sulfofuran-5-yl)nitroneYield 84.3%

Procedure

Following the procedure of Example 1 above and using 5-formylfuran-2-sulfonic acid, sodium salt hydrate and N-cyclohexylhydroxylamine, the title compound was prepared in 84.3% yield as the sodium salt, m.p. 236.1° C. (dec.).

Sources & evidence

ORD record
ord-a798daf75f9c4f22aeb10df6d1d8d53e
Source dataset
uspto-grants-2000_04
Patent number
US06051571

Reaction notes

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