HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(3-(benzyloxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine → 3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(3-(benzyloxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine | HCID 18792891 | — |
| Reactant | 5-(4-benzyloxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine | HCID 22736170 | — |
| Reactant | 3-(Toluene-4-sulfonylmethyl)-pyrrolidine-carboxylic acid tert-butyl ester | HCID 53718557 | — |
| Product | 3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester | HCID 44381608 | — |
Reaction Steps
Examples 63 and 64 are prepared analogously to Example 20/21 starting from 5-(4-benzyloxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl-amine or 5-(3-benzyloxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl-amine and 3-(toluene-4-sulfonylmethyl)-pyrrolidine-carboxylic acid tert-butyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06051577 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-391884e8904b493882ac2a1d5afb30a9 |
| Source note | uspto-grants-2000_04 |