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HRID1005000

反应详情

EQUATION

反应方程式

HRID 1005000 的结构方程式

REACTANTS

反应物

2
结构：BrCc1ccc2ccccc2c1
HCID70320

2-Bromomethylnaphthalene

C11H9Br

结构：COC(=O)c1ccc(C2CCN(C(=O)OC(C)(C)C)CC2O)cc1
HCID53949513

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2ccc3ccccc3c2)cc1
HCID54007898

未命名化合物

PROCEDURE

实验过程

In an analogous manner to that described in Example 22(i), by alkylating tert-butyl (3RS,4RS)-3-hydroxy-4-(4-methoxycarbonyl-phenyl)-piperidine-1-carboxylate with 2-bromomethylnaphthalene there was obtained tert-butyl (3RS,4RS)-4-(4-methoxycarbonyl-phenyl)-3-naphthalen-2-ylmethoxy-piperidine-1-carboxylate as a colourless oil; MS: 476 (M+H)+.