Sodium Acetate → HCID 18790891, compound

HRID 1005260Notes

Reaction equation

HRID 1005260 reaction equation
[CH2:1]([CH:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][O:13][Si:14]([C:17]([CH3:20])([CH3:19])[CH3:18])([CH3:16])[CH3:15])[CH2:6][OH:7])[CH2:2][CH2:3][CH3:4].[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1.C([O-])(=O)C.[Na+]>ClCCl>[CH2:1]([CH:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][O:13][Si:14]([C:17]([CH3:18])([CH3:20])[CH3:19])([CH3:15])[CH3:16])[CH:6]=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 18790894HCID 18790894, compoundHCID 178418287HCID 178418287, compound

Product 1

HCID 18790891HCID 18790891, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

A solution of 2-butyl-7-(tert-butyldimethylsilyloxy)-1-heptanol in dichloromethane (10 ml) was added to a suspension of pyridinium chlorochromate (8.09 g, 38 mmol) and sodium acetate (150 mg) in 30 ml of dichloromethane and stirred at ambient temperature for several hours. After the usual work up followed by PMPLC, 6.61 g (88%) of 2-butyl-7-(tert-butyldimethylsilyloxy)heptanaI was obtained.

Sources & evidence

ORD record
ord-50fe6a3c57db42ccbdfb0a9c3b6d0595
Source dataset
uspto-grants-2000_04
Patent number
US06054141

Reaction notes

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