反应详情

温度

20 °C

5.7 g (41 nmol) of gaseous hexafluoro-2-butyne were passed at below (-50)° C. into a suspension, cooled to (-70)° C., of 9 g (36 mmol) of α-bromo-4-chlorobenzaldehyde methylhydrazone in 100 ml of toluene. The mixture was subsequently heated to (-25)° C., and 8.4 g (83 mmol) of triethylamine were added dropwise at this temperature. After the mixture had been stirred for 2 hours at this temperature and for a further 16 hours at approx. 20° C., it as washed with water, dried over magnesium sulfate and finally concentrated.

1. temperatureinto a suspension, cooled to (-70)° C
2. temperatureThe mixture was subsequently heated to (-25)° C
3. washit as washed with water
4. dry with materialdried over magnesium sulfate
5. concentrationfinally concentrated