Methylhydrazine → HCID 67650044, compound

HRID 1005280Notes

Reaction equation

HRID 1005280 reaction equation
[CH3:1][NH:2][NH2:3].[Cl:4][C:5]1[CH:12]=[CH:11][C:8]([CH:9]=O)=[C:7]([F:13])[CH:6]=1>C(O)C>[CH3:1][NH:2][N:3]=[CH:9][C:8]1[CH:11]=[CH:12][C:5]([Cl:4])=[CH:6][C:7]=1[F:13]

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 27249084-Chloro-2-fluorobenzaldehyde

Product 1

HCID 67650044HCID 67650044, compoundYield 94%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

5.5 g (0.12 mol) of methylhydrazine were added to a solution of 19 g (0.12 mol) of 4-chloro-2-fluorobenzaldehyde in 120 ml of ethanol. After 1 hour, the mixture was concentrated, and the residue was subsequently treated with ethyl acetate. The organic phase was washed with water, dried over magnesium sulfate and finally concentrated. Yield: 94%

Workup

  1. concentrationthe mixture was concentrated
  2. additionthe residue was subsequently treated with ethyl acetate
  3. washThe organic phase was washed with water
  4. dry with materialdried over magnesium sulfate
  5. concentrationfinally concentrated

Sources & evidence

ORD record
ord-b1535c9a0e3d493bbd5a5071f86d6458
Source dataset
uspto-grants-2000_04
Patent number
US06054412

Reaction notes

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