Hydrochloric Acid → 8-Methyl-4-ethoxy-1,1-dioxothiochroman-7-carboxylic acid

Participants

Reaction Conditions

Reaction Steps

0.88 g (9 mmol) of ethylhydroxylamine is initially introduced in 20 ml of methanol. 0.62 g (4.5 mmol) of potassium carbonate is then added, followed by 2.0 g (9 mmol) of 8-methylthiochroman-4-one-7-carboxylic acid. The reaction is stirred at about 20° C. for 10 days. It is worked up by addition of water and 2N hydrochloric acid, and the resulting precipitate is filtered of f with suction and dried.

Provenance & Evidence