HCID 18791134, compound → HCID 18791114, compound

Participants

Reaction Conditions

Reaction Steps

A stirred mixture of 5-[3,3-di(ethoxycarbonyl) cyclobutyl]-5-(2,2-diphenylethyl)imidazolidine-2,4-dione (1.7 mmol) in 1M sodium hydroxide (17 ml) was heated to 70° C. for 2 hours. The cooled solution was filtered and the filtrate acidified with 5M hydrochloric acid (4 ml). The mixture was extracted with diethyl ether (30 ml) ethanol (3 ml) to give the title product as a white foam.

Provenance & Evidence