HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[5-(3,5-Dichloro-phenylsulfanyl)-4-isopropyl-2-methyl-imidazol-1-ylmethoxy]-ethanol → 1-[2-(Cycloocten-1-yloxy)ethoxymethyl]-5-(3, 5-dichlorophenylthio)-4-isopropyl-2-methyl-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[5-(3,5-Dichloro-phenylsulfanyl)-4-isopropyl-2-methyl-imidazol-1-ylmethoxy]-ethanol | HCID 478181 | — |
| Reactant | 1-Methoxycyclooct-1-ene | HCID 42586710 | — |
| Product | 1-[2-(Cycloocten-1-yloxy)ethoxymethyl]-5-(3, 5-dichlorophenylthio)-4-isopropyl-2-methyl-1H-imidazole | HCID 478182 | 70% |
Reaction Steps
The compound 8 (450 mg, 1.2 mmol) was converted to the enol ether with 1-methoxycyclooctene (1.51 g, 12 mmol) in the same manner as the example 10 to give the compound 11 (405 mg, 70%) as oil. Rf 0.50 (Al2O3 60, Type E, 10:1 toluene -EtOAc).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06054591 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-627dbcfa11da42ee81008abdfd7fd86e |
| Source note | uspto-grants-2000_04 |