HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[5-(3,5-Dichloro-phenylsulfanyl)-4-isopropyl-2-methyl-imidazol-1-ylmethoxy]-ethanol → 1-[2-(Cyclodecen-1-yloxy)ethoxymethyl]-5-(3,5-dichlorophenylthio)-4-isopropyl-2-methyl-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[5-(3,5-Dichloro-phenylsulfanyl)-4-isopropyl-2-methyl-imidazol-1-ylmethoxy]-ethanol | HCID 478181 | — |
| Reactant | 1-Methoxycyclodecene | HCID 522702 | — |
| Product | 1-[2-(Cyclodecen-1-yloxy)ethoxymethyl]-5-(3,5-dichlorophenylthio)-4-isopropyl-2-methyl-1H-imidazole | HCID 54080414 | 66% |
Reaction Steps
The compound 8 (375 mg, 1 mmol) was converted to the enol ether with 1-methoxy-1-cyclodecene (505 mg, 3 mmol) in the same manner as the example 10 to give the compound 12 (336 mg, 66%) as oil. Rf 0.55 (Al2O3 60, Type E, 10:1 toluene - EtOAc).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06054591 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-8bdfb4b407184d29b5cb5417a9852255 |
| Source note | uspto-grants-2000_04 |