HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbamate → 5-(3,5-Dichlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazol-2-ylmethyl palmitoylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbamate | HCID 276 | — |
| Reactant | (5-(3,5-Dichlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazol-2-yl)methanol | HCID 473933 | — |
| Reactant | Palmitoyl isocyanate | HCID 18792000 | — |
| Product | 5-(3,5-Dichlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazol-2-ylmethyl palmitoylcarbamate | HCID 69686480 | 57% |
Reaction Steps
The compound 19 (250 mg, 0.725 mmol) was converted to the carbamate with palmitoyl isocyanate (5 eq.) in the same manner as the example 66 to give the compound 85 (259 mg, 57%). Mp. 95-97° C. Rf 0.33 (1:2 EtOAc - hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06054591 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-5d912f3f93464a7dbab55e98775b76b9 |
| Source note | uspto-grants-2000_04 |