HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbamate → 5-(3,5-Dichlorophenylthio)-4-isopropyl-1-(4-pyridylmethyl)-1H-imidazol-2-ylmethyl myristoylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbamate | HCID 276 | — |
| Reactant | {5-[(3,5-Dichlorophenyl)sulfanyl]-4-isopropyl-1-((pyridin-4-YL)methyl)imidazol-2-YL}methanol | HCID 9844329 | — |
| Reactant | HCID 18792057 | HCID 18792057 | — |
| Product | 5-(3,5-Dichlorophenylthio)-4-isopropyl-1-(4-pyridylmethyl)-1H-imidazol-2-ylmethyl myristoylcarbamate | HCID 69689012 | 46% |
Reaction Steps
The compound 89 (245 mg, 0.6 mmol) was converted to the carbamate with myristoyl isocyanate (5 eq.) in the same manner as the example 66 to give the compound 94 (182 mg, 46%) as oil. Rf 0.41 (EtOAc).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06054591 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-96cfbe9e7b5241499fc6a48d123ef6e9 |
| Source note | uspto-grants-2000_04 |