Hydrochloric Acid → HCID 10109509, compound

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Reaction Steps

The compound was prepared by coupling of 2-pyridylacetic acid with 4-acetyl-2-(R,S)-[(1-pyrrolidinyl)methyl]piperazine; mp: (HCl salt) 127-130° C.; 1H NMR (free base, 200 MHz, CDCl3) δ1.4-1.7 (4 H, m), 2.0 (3 H, s), 2.2-3.2 (9 H, m), 3.4-4.8 (6 H, m), 6.8-7.5 (3 H, m), 8.4 (1 H, m); MS (FAB) 331 (M+H)+ ; Anal. Calcd. for C18H26N4O2.2HCl. 0.5 NH4Cl: C, 50.27; H, 7.03; N, 14.65. Found: C, 50.86; H, 6.47; N, 15.79.

Provenance & Evidence