HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 22674466, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 22674383 | HCID 22674383 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 22674466 | HCID 22674466 | 77% |
Reaction Steps
A solution of 2-(2-butoxycarbonylaminoethylamino)thieno[3,2-d]pyrimidin-4-yl 2-thienylmethanone (58 mg, 0.14 mmol) in MeOH (5 mL) was treated with 4-M HCl in dioxane (0.5 mL), stirred at room temperature for 16 h and the resulting solid filtered and washed with ether to give the title compound (41 mg, 77%) as a white crystalline solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06787541B1 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-6e75937168a246419193d4998cb1c85a |
| Source note | uspto-grants-2004_09 |