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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1005715Generated: November 1, 2026

Hydrochloric Acid → HCID 22674368, compound

https://huagongshe.com/reaction/1005715

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 22674421HCID 22674421—
SolventMethanolHCID 887—
SolventWaterHCID 962—
ProductHCID 22674368HCID 2267436850%

Reaction Steps

A solution of ethyl 4-(2-thienylcarbonyl)thieno[3,2-d]pyrimidine-2-carboxylate (80 mg, 0.25 mmol) in MeOH (3 mL) was treated with 2M-NaOH (1 mL), stirred at room temperature for 20 min, acidified with 1M-HCl, diluted with water and filtered to give the title compound (36 mg, 50%) as a pale yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06787541B1
Source datasetuspto-grants-2004_09
ORD IDord-e59f9990e00240438bac97894d704ee6
Source noteuspto-grants-2004_09