HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 6-Amino-3-methoxy-2-pyrazinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Methyl 6-amino-3-methoxy-2-pyrazinecarboxylate | HCID 22662843 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-Amino-3-methoxy-2-pyrazinecarboxamide | HCID 22662802 | — |
Reaction Steps
In 70 mL of methanol is dissolved 3.50 g of methyl 6-amino-3-methoxy-2-pyrazinecarboxylate. Gaseous ammonia is introduced to saturate the solution with ammonia. The solution is stirred at ambient temperature for 14 hours. The solvent is distilled off from the reaction mixture under reduced pressure to obtain 3.1 g of 6-amino-3-methoxy-2-pyrazinecarboxamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06787544B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-8945073da1d74c91b7401f03e7d09e37 |
| Source note | uspto-grants-2004_09 |