Ammonia → 89032-88-2

HRID 1005737Notes

Reaction equation

HRID 1005737 reaction equation
[OH:1][C:2]1[N:3]=[N:4][C:5]([C:9]([OH:11])=O)=[C:6]([OH:8])[N:7]=1.[NH3:12]>CN(C)C=O>[O:1]=[C:2]1[NH:7][C:6](=[O:8])[C:5]([C:9]([NH2:12])=[O:11])=[N:4][NH:3]1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 178524937HCID 178524937, compound

Product 1

HCID 1326667089032-88-2

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In 10 mL of dimethylformamide is suspended 0.5 g of 3,5-dihydroxy-1,2,4-triazine-6-carboxylic acid obtained according to the method described in literature (JP-A-54-79292). Then, 2.06 g of N,N′-carbonyldiimidazole is added thereto, and the resulting solution in stirred at ambient temperature for 6 hours. The reaction mixture is cooled with ice, saturated with gaseous ammonia, and then stirred for 15 minutes at the same temperature as above. The deposited crystals are collected by filtration to obtain 0.37 g of 3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxamide.

Workup

  1. customobtained
  2. stirringstirred for 15 minutes at the same temperature as above
  3. filtrationThe deposited crystals are collected by filtration

Sources & evidence

ORD record
ord-e0e5166cd51b4031905e7166624b5ca8
Source dataset
uspto-grants-2004_09
Patent number
US06787544B2

Reaction notes

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