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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1005896Generated: November 1, 2026

2-[4-(4-furan-2-yl-phenyl)piperazine-1-sulfonylmethyl]-N-hydroxy-3-methylbutyramide → 2-[4-(4-Pyridin-3-yl-phenyl)piperazine-1-sulfonylmethyl]-N-hydroxy-3-methylbutyramide

https://huagongshe.com/reaction/1005896

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[4-(4-furan-2-yl-phenyl)piperazine-1-sulfonylmethyl]-N-hydroxy-3-methylbutyramideHCID 9931969—
Reactant3-Methyl-2-[4-(4-pyridin-3-yl-phenyl)piperazine-1-sulfonylmethyl]butyric acidHCID 22646734—
Product2-[4-(4-Pyridin-3-yl-phenyl)piperazine-1-sulfonylmethyl]-N-hydroxy-3-methylbutyramideHCID 1013768076%

Reaction Steps

Prepared according to the method for the preparation of 2-[4-(4-furan-2-yl-phenyl)piperazine-1-sulfonylmethyl]-N-hydroxy-3-methylbutyramide, from 3-methyl-2-[4-(4-pyridin-3-yl-phenyl)piperazine-1-sulfonylmethyl]butyric acid (0.075 g), to yield the title compound as a white solid (0.059 g, 76%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06787536B2
Source datasetuspto-grants-2004_09
ORD IDord-3a66d01aab1f4ddb8590e08f43608c16
Source noteuspto-grants-2004_09