反应详情

A solution of 2,4-thiazolidinedione (120 mg) and 4-[2-(N-methyl-N-(6-(4-anilinyl)pyrimidinyl)amino)ethoxy]benzaldehyde (280 mg) in a catalytic amount of piperidinium acetate containing toluene (60 mL), was stirred under reflux on a Dean-stark device for 4 hours. The resultant mixture was cooled and filtered. The filtered solid was dried to give the title compound (250 mg).

1. temperatureunder reflux on a Dean-stark device for 4 hours
2. filtrationfiltered
3. customThe filtered solid was dried