HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiazolidinedione → HCID 73889972, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiazolidinedione | HCID 5437 | — |
| Reactant | Piperidinium acetate | HCID 3014295 | — |
| Reactant | HCID 22675140 | HCID 22675140 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 73889972 | HCID 73889972 | 69.5% |
Reaction Steps
A solution of 2,4-thiazolidinedione (120 mg) and 4-[2-(N-methyl-N-(6-(4-anilinyl)pyrimidinyl)amino)ethoxy]benzaldehyde (280 mg) in a catalytic amount of piperidinium acetate containing toluene (60 mL), was stirred under reflux on a Dean-stark device for 4 hours. The resultant mixture was cooled and filtered. The filtered solid was dried to give the title compound (250 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06787551B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-db52b00ed3734b4b9a47e1d603c82476 |
| Source note | uspto-grants-2004_09 |