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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1005915Generated: October 31, 2026

Thiazolidinedione → HCID 73889972, compound

https://huagongshe.com/reaction/1005915

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiazolidinedioneHCID 5437—
ReactantPiperidinium acetateHCID 3014295—
ReactantHCID 22675140HCID 22675140—
SolventTolueneHCID 1140—
ProductHCID 73889972HCID 7388997269.5%

Reaction Steps

A solution of 2,4-thiazolidinedione (120 mg) and 4-[2-(N-methyl-N-(6-(4-anilinyl)pyrimidinyl)amino)ethoxy]benzaldehyde (280 mg) in a catalytic amount of piperidinium acetate containing toluene (60 mL), was stirred under reflux on a Dean-stark device for 4 hours. The resultant mixture was cooled and filtered. The filtered solid was dried to give the title compound (250 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06787551B2
Source datasetuspto-grants-2004_09
ORD IDord-db52b00ed3734b4b9a47e1d603c82476
Source noteuspto-grants-2004_09