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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1005987Generated: October 31, 2026

2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoyl chloride → HCID 10166611, compound

https://huagongshe.com/reaction/1005987

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoyl chlorideHCID 11267141—
ReactantHCID 22674327HCID 22674327—
ProductHCID 10166611HCID 10166611—

Reaction Steps

The resulting [4-(2-chloro-phenoxy)-2-methylsulfanyl-pyrimidin-5-yl]-methyl-amine was treated with 2-(3,5-bis-trifluormethyl-phenyl)-2-methyl-propionyl chloride as described in Example 43e) to give 2-(3,5-bis-trifluoromethyl-phenyl)-N-[4-(2-chloro-phenoxy)-2-methylsulfanyl-pyrimidin-5-yl]-N-methyl-isobutyramide as a white foam, MS (ISP): 564.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06787539B2
Source datasetuspto-grants-2004_09
ORD IDord-5675ed36de37463e8f6a262d151b8f99
Source noteuspto-grants-2004_09