HRID1006241

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：O=C(c1ccc(Br)cc1)N1CCN(CCCN2CCN(C(=O)c3ccc(Br)cc3)CC2)CC1

HCID11692723

未命名化合物

HCID22485542

未命名化合物

PRODUCTS

产物

反应SMILES：CCCOc1c(OC)cc(-c2ccc(C(=O)N3CCN(CCCN4CCN(C(=O)c5ccc(-c6cc(OC)c(OCCC)c(OC)c6)cc5)CC4)CC3)cc2)cc1OC

HCID10259962

未命名化合物

收率 100%

PROCEDURE

实验过程

By similar procedures applied in Example 2, from 3.00 g (5.19 mmol) of 1,3-bis [4-(4-bromobenzoyl)-1-piperazinyl]propane and 3.00 g (12.5 mmol) of 3,5-dimethoxy-4-propoxyphenylboronic acid, 4.20 g of 1,3-bis[4[4-(3,5-dimethoxy-4-propoxyphenyl) benzoyl]-1-piperazinyl]propane was obtained as a colorless oil (quantitative yield).

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-c05c0803c6a94cbfb552f7685a23d8bf
来源数据集: uspto-grants-2004_09
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US06787653B2
来源说明: uspto-grants-2004_09

反应SMILES

Br[C:2]1[CH:33]=[CH:32][C:5]([C:6]([N:8]2[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][N:17]3[CH2:22][CH2:21][N:20]([C:23](=[O:31])[C:24]4[CH:29]=[CH:28][C:27](Br)=[CH:26][CH:25]=4)[CH2:19][CH2:18]3)[CH2:10][CH2:9]2)=[O:7])=[CH:4][CH:3]=1.[CH3:34][O:35][C:36]1[CH:37]=[C:38](B(O)O)[CH:39]=[C:40]([O:46][CH3:47])[C:41]=1[O:42][CH2:43][CH2:44][CH3:45]>>[CH3:34][O:35][C:36]1[CH:37]=[C:38]([C:2]2[CH:33]=[CH:32][C:5]([C:6]([N:8]3[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][CH2:16][N:17]4[CH2:18][CH2:19][N:20]([C:23](=[O:31])[C:24]5[CH:25]=[CH:26][C:27]([C:38]6[CH:37]=[C:36]([O:35][CH3:34])[C:41]([O:42][CH2:43][CH2:44][CH3:45])=[C:40]([O:46][CH3:47])[CH:39]=6)=[CH:28][CH:29]=5)[CH2:21][CH2:22]4)[CH2:12][CH2:13]3)=[O:7])=[CH:4][CH:3]=2)[CH:39]=[C:40]([O:46][CH3:47])[C:41]=1[O:42][CH2:43][CH2:44][CH3:45]