HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Bis[4-(4-bromobenzoyl)-1-piperazinyl]propane → 1,3-Bis[4-[4-(3,5-dimethoxy-4-propoxyphenyl) benzoyl]-1-piperazinyl]propane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Bis[4-(4-bromobenzoyl)-1-piperazinyl]propane | HCID 11692723 | — |
| Reactant | 3,5-Dimethoxy-4-propoxyphenylboronic acid | HCID 22485542 | — |
| Product | 1,3-Bis[4-[4-(3,5-dimethoxy-4-propoxyphenyl) benzoyl]-1-piperazinyl]propane | HCID 10259962 | 100% |
Reaction Steps
By similar procedures applied in Example 2, from 3.00 g (5.19 mmol) of 1,3-bis [4-(4-bromobenzoyl)-1-piperazinyl]propane and 3.00 g (12.5 mmol) of 3,5-dimethoxy-4-propoxyphenylboronic acid, 4.20 g of 1,3-bis[4[4-(3,5-dimethoxy-4-propoxyphenyl) benzoyl]-1-piperazinyl]propane was obtained as a colorless oil (quantitative yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06787653B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-c05c0803c6a94cbfb552f7685a23d8bf |
| Source note | uspto-grants-2004_09 |