HCID 86600020, compound → HCID 44474956, compound

HRID 1006502Notes

Reaction equation

HRID 1006502 reaction equation
[NH2:1][C:2](=O)[C@H:3]([NH:5][C:6](=[O:22])[O:7][CH2:8][CH:9]1[C:21]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[C:15]2[C:10]1=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH3:4]>C1COCC1>[NH2:1][CH2:2][C@H:3]([NH:5][C:6](=[O:22])[O:7][CH2:8][CH:9]1[C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=2[C:16]2[C:21]1=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH3:4]

Participants

3

Reactant 1

HCID 86600020HCID 86600020, compound

Product 1

HCID 44474956HCID 44474956, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To a solution of the product from example 25 step a) (6.9 g) in THF (100 ml) was added boran-methylsulfide complex (4.4 ml) and the mixture heated under reflux for 2 hours.

Workup

  1. temperaturethe mixture heated
  2. temperatureunder reflux for 2 hours

Sources & evidence

ORD record
ord-6684b5c53b5f43c69b1bfeef6cb7e50b
Source dataset
uspto-grants-2004_09
Patent number
US06790850B1

Reaction notes

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