Dimethylamine → HCID 23378634, compound

Participants

Reaction Steps

To a solution of 4-[2-(N-methoxymethoxycarbonylmethyl-phenylsulfonylamino)-5-trifluoromethylphenoxymethyl]benzoic acid. methoxymethyl ester (476 mg; prepared in Reference Example 35) in THF (2 ml), dimethylamine(0.8 ml) was added. The mixture was stirred for 3 days at room temperature. The solvent was distilled off. The residue was purified on silica gel column chromatography (hexane:AcOEt=2:1→1:1) to give the title compound (290 mg) having the following physical data.

Provenance & Evidence