Bromoacetyl bromide → 2-Bromo-N-isopropyl-N-methyl-acetamide

Temperature

-20 °C

A solution of 26 ml of methyl isopropylamine in 100 ml of ether was added to a solution of 10 ml of bromo acetyl bromide in 150 ml of ether cooled to −20° C. and the mixture was allowed to return to 20° C. The mixture was stirred for 30 minutes at 20° C. and diluted with water, decanted and extracted with ether. The extracts were dried and separated out by distillation to obtain 13 g of the expected product with a boiling point of 71° C. to 72° C. under 1 mmHg.

1. customto return to 20° C
2. customdecanted
3. extractionextracted with ether
4. customThe extracts were dried
5. customseparated out by distillation

ORD record

ord-3dc4b506b8d643bbaf7373f0fa4412b9

Source dataset

uspto-grants-2004_09

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US06790971B1