Water → HCID 22502974, compound

HRID 1006926Notes

Reaction equation

HRID 1006926 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]#[C:10][C:11]2[CH:12]=[N:13][CH:14]=[CH:15][C:16]=2[CH:17]=[N:18][OH:19])=[CH:5][CH:4]=1.C(=O)([O-])[O-].[K+].[K+].O>C(O)C>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N+:18]([O-:19])=[CH:17][C:16]3[C:11]([CH:10]=2)=[CH:12][N:13]=[CH:14][CH:15]=3)=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 962WaterHCID 11430Potassium CarbonateHCID 136343617HCID 136343617, compound

Product 1

HCID 22502974HCID 22502974, compoundYield 79.5%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
70 °C

Procedure

3-(4-Methoxyphenylethynyl)-4-pyridine aldoxime (4.724 g) was dissolved in ethanol (100 ml), followed by the addition of potassium carbonate (2.768 g)/water (30 ml) solution, and the mixture was stirred at 70° C. for 50 min. After cooling as it was, the resulting insoluble matters were collected by filtration, and then washed with water and ethanol, to give the title compound as a dark green solid (3.757 g, yield; 75%).

Workup

  1. temperatureAfter cooling as it
  2. filtrationthe resulting insoluble matters were collected by filtration
  3. washwashed with water and ethanol

Sources & evidence

ORD record
ord-864a9a8eb815428c84b2bbcd8a4eaf68
Source dataset
uspto-grants-2004_09
Patent number
US06790844B2

Reaction notes

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