Hydrochloric Acid → 3-[({4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}methyl)(ethyl)amino]-1-methylazetidine-3-carboxamide

HRID 100694Notes

Reaction equation

HRID 100694 reaction equation
[CH2:34]=[O:35].[Cl:2][c:3]1[c:4]([F:33])[c:5]([NH:9][c:10]2[n:11][cH:12][n:13][c:14]3[cH:15][c:16]([O:31][CH3:32])[c:17]([CH2:20][N:21]([C:22]4([C:26](=[O:27])[NH2:28])[CH2:23][NH:24][CH2:25]4)[CH2:29][CH3:30])[cH:18][c:19]23)[cH:6][cH:7][cH:8]1.[ClH:1]>>[Cl:2][c:3]1[c:4]([F:33])[c:5]([NH:9][c:10]2[n:11][cH:12][n:13][c:14]3[cH:15][c:16]([O:31][CH3:32])[c:17]([CH2:20][N:21]([C:22]4([C:26](=[O:27])[NH2:28])[CH2:23][N:24]([CH3:34])[CH2:25]4)[CH2:29][CH3:30])[cH:18][c:19]23)[cH:6][cH:7][cH:8]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 712FormaldehydeHCID 579798383-[[4-(3-Chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]methyl-ethylamino]azetidine-3-carboxamide

Product 1

HCID 579798813-[({4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}methyl)(ethyl)amino]-1-methylazetidine-3-carboxamide

Sources & evidence

ORD record
ord-8834d526cf5e4bedb589f1a618b749b0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…