反应详情

The compound is prepared starting from a solution of Pyrazinamide (2 g, 16.24 mmoles) in a mixture of acetonitrile (30 ml)/tetrahydrofuran (30 ml), by adding a 65% nitric acid solution (1.2 ml) in acetonitrile (5 ml), following then the procedure described in Example 5. Pyrazinamide nitrate salt as amorphous solid is obtained. Yield 74%.

1. customThe compound is prepared