5-bromo-4-methoxy-2-nitroaniline → HCID 10200191, compound

HRID 1007180Notes

Reaction equation

HRID 1007180 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][N:3]=1.[Br:11][C:12]1[CH:13]=[C:14]([C:16]([N+:21]([O-:23])=[O:22])=[CH:17][C:18]=1[O:19][CH3:20])[NH2:15]>>[Cl:1][C:2]1[N:3]=[CH:4][C:5]([C:6]([NH:15][C:14]2[C:16]([N+:21]([O-:23])=[O:22])=[CH:17][C:18]([O:19][CH3:20])=[C:12]([Br:11])[CH:13]=2)=[O:7])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 2441565-bromo-4-methoxy-2-nitroanilineHCID 27821656-Chloronicotinoyl Chloride

Product 1

HCID 10200191HCID 10200191, compound

Procedure

The title compound was prepared from 6-chloronicotinoyl chloride and 3-bromo-4-methoxy-6-nitroaniline and was obtained as a yellow solid as described in Example 1. 1H NMR (DMSO-d6): 10.84 (s, 1H), 8.93 (d, J=2.4, 1H), 8.34-8.30 (m, 1H), 7.98 (s, 1H), 7.76 (d, J=8.4, 1H), 7.70 (s, 1H), 3.97 (s, 3H).

Workup

  1. customwas obtained as a yellow solid

Sources & evidence

ORD record
ord-e405d5698aaa4e05a1bf992f7aa4eb35
Source dataset
uspto-grants-2004_09
Patent number
US06794397B2

Reaction notes

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