HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-4-methoxyaniline → 6-Chloro-N-(4-methoxy-2-methyl-phenyl)-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-4-methoxyaniline | HCID 7610 | — |
| Reactant | 6-Chloronicotinoyl Chloride | HCID 2782165 | — |
| Product | 6-Chloro-N-(4-methoxy-2-methyl-phenyl)-nicotinamide | HCID 9856843 | — |
Reaction Steps
The title compound was prepared from 6-chloronicotinoyl chloride and 4-methoxy-2-methylaniline and was obtained as a white solid as described in Example 1. 1H NMR (CDCl3): 8.88 (bs, 1H), 8.19 (d, J=7.2, 1H), 7.61-7.47 (m, 3H), 6.81-6.79 (m, 2H), 3.81 (s, 3H), 2.30 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06794397B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-0876b758cc204d87af352f6d1cbde6bf |
| Source note | uspto-grants-2004_09 |