2-Amino-5-chlorobenzonitrile → HCID 9814573, compound

HRID 1007209Notes

Reaction equation

HRID 1007209 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][N:3]=1.[NH2:11][C:12]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:13]=1[C:14]#[N:15]>>[Cl:1][C:2]1[N:3]=[CH:4][C:5]([C:6]([NH:11][C:12]2[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:13]=2[C:14]#[N:15])=[O:7])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 800192-Amino-5-chlorobenzonitrileHCID 27821656-Chloronicotinoyl Chloride

Product 1

HCID 9814573HCID 9814573, compound

Procedure

The title compound was prepared from 6-chloronicotinoyl chloride and 2-amino-5-chlorobenzonitrile as a white solid as described in Example 1. 1H NMR (CDCl3): 8.96 (d, J=2.7, 1H), 8.53-8.50 (M, 1H), 8.24 (s, 1H), 8.19-8.15 (m, 1H), 7.67-7.63 (m, 2H), 7.54-7.51 (m, 1H).

Sources & evidence

ORD record
ord-e229b2d4a6f7496698751e7e4f7e93b8
Source dataset
uspto-grants-2004_09
Patent number
US06794397B2

Reaction notes

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