HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy-3-pyridinylamine → 6-Chloro-N-(6-methoxypyridin-3-YL)pyridine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy-3-pyridinylamine | HCID 81121 | — |
| Reactant | 6-Chloronicotinoyl Chloride | HCID 2782165 | — |
| Product | 6-Chloro-N-(6-methoxypyridin-3-YL)pyridine-3-carboxamide | HCID 22668926 | — |
Reaction Steps
The title compound was prepared from 6-chloronicotinoyl chloride and 5-amino-2-methoxypyridine as a pink solid as described in Example 1. 1H NMR (CDCl3): 8.87 (d, J=2.1, 1H), 8.28 (d, J=3.0, 1H), 8.20-8.17 (m, 1H), 7.99-7.96 (m, 1H), 7.67 (s, 1H), 7.49 (d, J=8.7, 1H), 6.81 (d, J=8.7, 1H), 3.95 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06794397B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-10dfa030828b40d884740f7175c280c4 |
| Source note | uspto-grants-2004_09 |