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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1007312Generated: October 31, 2026

Hydrochloric Acid → HCID 178478702, compound

https://huagongshe.com/reaction/1007312

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 11057974HCID 11057974—
SolventMethanolHCID 887—
ProductHCID 178478702HCID 17847870283%

Reaction Conditions

Temperature60 °C

Reaction Steps

To a solution of N-triphenylmethyl-4-(trans-2-aminomethyl-cyclopropyl)imidazole (100 mg, 0.26 mmol) in methanol (15 mL) was added 2N HCl solution (2.5 mL). The mixture was stirred at 60° C. for 2 hours and then concentrated. The resulting residue was extracted with ether (3×20 ml). The aqueous layer was lyophilized to give the product (47 mg, 83% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06794405B2
Source datasetuspto-grants-2004_09
ORD IDord-b4fac3a3f7af44e7b443dac7fa09548e
Source noteuspto-grants-2004_09