p-Anisoyl chloride → 2-(4-Hydroxyphenyl)-5-benzoxazolol

HRID 1007327Notes

Reaction equation

HRID 1007327 reaction equation
[CH3:1][O:2][C:3]1[CH:9]=[CH:8][C:7]([O:10]C)=[CH:6][C:4]=1[NH2:5].C[O:13][C:14]1[CH:22]=[CH:21][C:17](C(Cl)=O)=[CH:16][CH:15]=1>>[OH:13][C:14]1[CH:22]=[CH:21][C:17]([C:1]2[O:2][C:3]3[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][C:4]=3[N:5]=2)=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 7477p-Anisoyl chlorideHCID 76132,5-Dimethoxyaniline

Product 1

HCID 1354057412-(4-Hydroxyphenyl)-5-benzoxazolol

Procedure

The title compound was prepared in substantially the same manner as described in Example 1, from 2,5-dimethoxyaniline, and 4-methoxybenzoyl chloride and was obtained as a light yellow solid, m.p. 264-267° C.; MS m/e 228 (M+H)+.

Workup

  1. customwas obtained as a light yellow solid, m.p. 264-267° C.

Sources & evidence

ORD record
ord-f359d97537dc4471b7c37049691ccbce
Source dataset
uspto-grants-2004_09
Patent number
US06794403B2

Reaction notes

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