HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → (2-Nitro-4-trifluorobenzyl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 69744202 | HCID 69744202 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (2-Nitro-4-trifluorobenzyl)acetic acid | HCID 74433 | — |
Reaction Steps
16.7 g of tert.butyl 2-nitro-4-trifluoromethyl-phenylacetate and 50 ml of trifluoroacetic acid are dissolved in 50 ml of methylene chloride and stirred for 3 hours at ambient temperature. After elimination of the solvent the residue is taken up in petroleum ether/ether (10:1), suction filtered and dried in vacuo at 80° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06794395B1 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-e9fc63dba6d546939d8eb45e618e2542 |
| Source note | uspto-grants-2004_09 |