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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 100741Generated: October 28, 2026

Hydrochloric Acid → 5-(6-Hydroxymethyl-pyrimidin-4-yloxy)-2,3-dihydro-indole-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide

https://huagongshe.com/reaction/100741

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
ReactantBorohydrideHCID 28123—
ReactantIsobutyl chloroformateHCID 62365—
ReactantHCID 59596375HCID 59596375—
Product5-(6-Hydroxymethyl-pyrimidin-4-yloxy)-2,3-dihydro-indole-1-carboxylic acid (3-trifluoromethyl-phenyl)-amideHCID 59596347—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-2d5e235eb5cc447d900d0ffda2c030cf
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)