Hydrochloric Acid → 5-(6-Hydroxymethyl-pyrimidin-4-yloxy)-2,3-dihydro-indole-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide
Reaction equation
[BH4-:48].[CH2:40]([O:41][C:42]([Cl:43])=[O:44])[CH:45]([CH3:46])[CH3:47].[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[CH3:56][CH2:57][O:58][C:59]([CH3:60])=[O:61].[ClH:62].[F:1][C:2]([c:3]1[cH:4][c:5]([NH:9][C:10](=[O:11])[N:12]2[CH2:13][CH2:14][c:15]3[cH:16][c:17]([O:21][c:22]4[cH:23][c:24]([C:28](=[O:29])[OH:30])[n:25][cH:26][n:27]4)[cH:18][cH:19][c:20]32)[cH:6][cH:7][cH:8]1)([F:31])[F:32].[Na+:49].[OH2:55]>>[F:1][C:2]([c:3]1[cH:4][c:5]([NH:9][C:10](=[O:11])[N:12]2[CH2:13][CH2:14][c:15]3[cH:16][c:17]([O:21][c:22]4[cH:23][c:24]([CH2:28][OH:29])[n:25][cH:26][n:27]4)[cH:18][cH:19][c:20]32)[cH:6][cH:7][cH:8]1)([F:31])[F:32]Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-2d5e235eb5cc447d900d0ffda2c030cf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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