反应详情

Preparation is carried out in analogy to the procedure of Example VII from 2.0 g (4.18 mmol) of benzyl alcohol derivative from Example XXI and 2.82 g (6.69 mmol) of dibromotriphenylphosphorane in 40 ml of acetonitrile. After stirring for 3 hours at room temperature, 0.3 equivalent of dibromotriphenylphosphorane is again added. The mixture is additionally stirred for 5 hours at 70° C. and afterwards overnight at room temperature. The purification of the product is carried out on silica gel using toluene as eluent.

1. customPreparation
2. stirringThe mixture is additionally stirred for 5 hours at 70° C. and afterwards overnight at room temperature
3. customThe purification of the product