Water → 2,3-Dichloro-N-[1-(methoxycarbonylmethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]-4H-thieno[3,2-b]pyrrole-5-carboxamide

HRID 100769Notes

Reaction equation

HRID 100769 reaction equation
[C:1](=[O:2])([OH:3])[c:4]1[cH:5][c:6]2[c:7]([nH:8]1)[c:9]([Cl:13])[c:10]([Cl:12])[s:11]2.[CH3:24][CH2:25][N:26]=[C:27]=[N:28][CH2:29][CH2:30][CH2:31][N:32]([CH3:33])[CH3:34].[Cl:35][c:36]1[s:37][c:38]2[nH:39][c:40]([C:41](=[O:42])[NH:45][CH:46]3[C:47](=[O:61])[N:48]([CH2:56][C:57](=[O:58])[O:59][CH3:60])[c:49]4[cH:50][cH:51][cH:52][cH:53][c:54]4[CH2:55]3)[cH:43][c:44]2[cH:62]1.[Cl:64][CH2:65][Cl:66].[OH2:63].[OH:14][n:15]1[c:16]2[c:17]([cH:18][cH:19][cH:20][cH:21]2)[n:22][n:23]1>>[C:1](=[O:3])([c:4]1[cH:5][c:6]2[c:7]([nH:8]1)[c:9]([Cl:13])[c:10]([Cl:12])[s:11]2)[NH:45][CH:46]1[C:47](=[O:61])[N:48]([CH2:56][C:57](=[O:58])[O:59][CH3:60])[c:49]2[cH:50][cH:51][cH:52][cH:53][c:54]2[CH2:55]1

Participants

7

Reactant 6

HCID 962WaterHCID 6344DichloromethaneHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 100020612-Chloro-N-[1-(methoxycarbonylmethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]-6H-thieno[2,3-b]pyrrole-5-carboxamideHCID 100143182,3-dichloro-4H-thieno[3,2-b]pyrrole-5-carboxylic acid

Product 1

HCID 104790032,3-Dichloro-N-[1-(methoxycarbonylmethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]-4H-thieno[3,2-b]pyrrole-5-carboxamide

Sources & evidence

ORD record
ord-95f5f548ca9e477483dde9dd039e8edd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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