Methanol → 3-[1-(5-Fluoro-2-methoxyphenyl)cycloprop-1-yl]-1-(2-methylquinolin-5-ylamino)-2-(trifluoromethyl)propan-2-ol
Reaction equation
[BH4-:33].[CH3:35][OH:36].[F:1][c:2]1[cH:3][cH:4][c:5]([O:31][CH3:32])[c:6]([C:8]2([CH2:11][C:12]([CH:13]=[N:14][c:15]3[c:16]4[cH:17][cH:18][c:19]([CH3:25])[n:20][c:21]4[cH:22][cH:23][cH:24]3)([OH:26])[C:27]([F:28])([F:29])[F:30])[CH2:9][CH2:10]2)[cH:7]1.[Na+:34].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:31][CH3:32])[c:6]([C:8]2([CH2:11][C:12]([CH2:13][NH:14][c:15]3[c:16]4[cH:17][cH:18][c:19]([CH3:25])[n:20][c:21]4[cH:22][cH:23][cH:24]3)([OH:26])[C:27]([F:28])([F:29])[F:30])[CH2:9][CH2:10]2)[cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-2183816ebbc042f89cb7db461f1038d0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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